INHIBITION OF THE MAMMALIAN TARGET OF RAPAMYCIN (MTOR) IN ADVANCED PANCREATIC CANCER: RESULTS OF TWO PHASE II STUDIES

Inhibition of the mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: results of two phase II studies

Abstract Background The phosphoinositide chewmax pet products chicken feet natural chew dog treats 3-kinase (PI3K)/Akt pathway is constitutively activated in pancreatic cancer and the mammalian target of rapamycin (mTOR) kinase is an important mediator for its signaling.Our recent in vitro studies suggest that prolonged exposure of pancreatic cance

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A novel method for efficient generation of antigen-specific effector T-cells using dendritic cells transduced with recombinant adeno-associated virus and p38 kinase blockade

Abstract Background The inefficacy of standard therapeutic strategies for ovarian cancer is reflected by the sd11i enduring poor prognosis of this malignancy.Due to the potential for exquisite specificity, sensitivity and long-term memory, immunotherapy offers an alternative modality for durable control of the disease, provided appropriate antigens

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Estimating Black Oat Biomass Using Digital Surface Models and a Vegetation Index Derived from RGB-Based Aerial Images

Responsible for food production and industry inputs, agriculture needs to adapt to worldwide increasing demands and environmental requirements.In this scenario, black sassafras dahlia oat has gained environmental and economic importance since it can be used in no-tillage systems, green manure, or animal feed supplementation.Despite its importance,

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Modeling method of phase equilibrium in metal-slag system

This paper demonstrates a new modeling method of the complex heterogeneous sd11i processes between a metal and slag based on a pattern of formation of the crystallization fields of phases.The theoretical justification was provided for the using of the osmotic coefficients of Bjerrum-Guggenheim with the reduction reactions of elements from the liqui

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